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Similar content being viewed by others Introduction Obesity is the modern epidemic, generally defined as a body mass index (BMI) 30 kg/m 2 , though a BMI 27.5 kg/m 2 defines obesity in Asian populations [1]

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In line with this finding, a different research discovered that changes in the SLC22A1 gene, responsible for OCT1, decreased the absorption of metformin in the liver without impacting the ability of metformin to lower glucose levels in individuals with T2DM (Zhou et al., 2009

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